Mu rwego rwo kurwanya iki cyorezo mu ntangiriro za 2020, mu minsi 35 gusa, hashyizweho icyitegererezo cy’imbeba ya ACE2 cy’umuntu, maze umushakashatsi Guangming Wu na bagenzi be bo mu kigo cy’ubushakashatsi bw’ibihe by’akagari (CCLA) muri Laboratwari ya Bio-Island bakora neza intambwe ikomeye ikoresheje ikorana buhanga mu gukora "kurwanya New Coronary Pneumonia".Igitangaza cyihuta mugitero cyihutirwa.
Ikizamini gitunguranye
Muri Kanama 2019, Wu Guangming, umushakashatsi umaze igihe kinini mu bijyanye no guteza imbere urusoro, yagarutse i Guangzhou avuye mu Budage kugira ngo yinjire mu cyiciro cya mbere cy '"Intara ya Guangdong kubaka itsinda ry’igihugu ry’ibigega bya laboratoire" rya Laboratoire ya Bio-Island, ari yo Laboratoire ya Guangzhou Guangdong yubuvuzi bushya nubuzima.
Icyo atari yiteze ni uko bitazatinda mbere yuko ahura n'ikizamini gitunguranye cy'icyorezo gishya cy'umusonga.
"Urwego rw'ubushakashatsi ndimo gukora mu by'ukuri ntaho ruhuriye n'indwara zandura, ariko imbere y'icyorezo cyegereje, nyuma yo kumenya ko ishami ry'ubumenyi n'ikoranabuhanga mu Ntara ya Guangdong ryashyizeho umushinga wihariye w'ubushakashatsi bwihutirwa ku ikamba rishya. icyorezo cy'umusonga, nibajije icyo nakora kugira ngo ndwanye iki cyorezo igihe igihugu cyose cyakoreraga hamwe. "
Binyuze mu gusobanukirwa, Wu Guangming yasanze icyitegererezo cy’inyamaswa gikenewe byihutirwa mu gusuzuma no kuvura coronavirus nshya ndetse no kugenzura igihe kirekire.Icyitwa inyamanswa y’inyamanswa ni ugukora inyamaswa (inkende, imbeba, nibindi) zifite ibintu bimwe na bimwe biranga ingirangingo zabantu, ingingo, ningirabuzimafatizo binyuze mu guhindura gene hamwe nubundi buryo bwo kubaka icyitegererezo cy’indwara, kwiga uburyo butera indwara z’abantu kandi ugasanga igisubizo cyiza cyo kuvura.
Igitero cyarangiye mu minsi 35
Wu Guangming yabwiye umunyamakuru ko muri kiriya gihe hariho moderi ya vitro selile gusa kandi abantu benshi bari bafite impungenge.Yabaye afite uburambe bwimyaka myinshi mubushakashatsi bwinyamanswa kandi yari umuhanga mubuhanga bwa tetraploid.Kimwe mu bitekerezo bye by'ubushakashatsi icyo gihe kwari uguhuza ikoranabuhanga rya embryonic stem selile na embryonic tetraploid indishyi hamwe hamwe kugirango habeho imiterere yimbeba zabantu, kandi byari bishimishije ko Ikigo cy’ubushakashatsi bw’amateka n’ibisekuru muri Laboratwari ya Bio Island cyari gifite ikoranabuhanga rikomeye ry’ingirabuzimafatizo. , kandi wasangaga ibintu byose byo hanze byari byeze.
Gutekereza ni ikintu kimwe, gukora ni ikindi.
Nibihe bigoye kubaka moderi ikoreshwa yimbeba?Mubikorwa bisanzwe, byatwara byibuze amezi atandatu kandi bikanyura mubigeragezo bitabarika.Ariko imbere yicyorezo cyihutirwa, umuntu akeneye kwiruka kumwanya no kumanika ku ikarita.
Iri tsinda ryashinzwe ku buryo budasanzwe kubera ko abantu benshi bari bamaze gutaha umwaka mushya w'Ubushinwa.Amaherezo, abantu umunani bagumye i Guangzhou basanze munsi y’ikigo cy’ubushakashatsi bw’akagari n’ibisekuru kugira ngo babe itsinda ry’ibitero by’imbeba by’agateganyo.
Kuva hategurwa protocole yubushakashatsi ku ya 31 Mutarama kugeza havutse igisekuru cya mbere cyimbeba zabantu ku ya 6 Werurwe, itsinda ryakoze iki gitangaza cyubushakashatsi bwa siyanse muminsi 35 gusa.Ikoranabuhanga risanzwe risaba kuvanga ingirangingo zimbeba ninsoro kugirango ubone imbeba za chimeric, kandi mugihe gusa ingirabuzimafatizo zitandukanije ingirabuzimafatizo hanyuma zigahuzwa nizindi mbeba kugirango zanduze genes zahinduwe kugeza ku gisekuru kizaza cyimbeba zishobora kubonwa ko zatsinze.Imbeba zabantu ziva muri CCLA zavutse kugirango zibone icyarimwe imbeba zo gukomanga icyarimwe, zibone umwanya wingenzi kandi zizigama abakozi nubutunzi bwo kurwanya icyorezo.
Wu Guangming kumurimo Ifoto / yatanzwe nuwabajijwe
Bose bakora amasaha y'ikirenga
Wu Guangming yemeye ko mu ntangiriro, nta muntu n'umwe wari ufite epfo na ruguru, kandi ikoranabuhanga rya tetraploid ubwaryo ryari rigoye cyane, aho gutsinda bitageze kuri 2%.
Muri kiriya gihe, abantu bose barihaye cyane ubushakashatsi, batitaye kumanywa nijoro, nta minsi y'akazi na wikendi.Buri munsi saa tatu cyangwa saa yine za mugitondo, abagize itsinda baganiriye ku iterambere ryumunsi;baraganiriye kugeza bucya bahita basubira kuwundi munsi w'ubushakashatsi.
Nkumuyobozi wa tekinike witsinda ryubushakashatsi, Wu Guangming agomba guhuza ibintu bibiri byakazi - gutunganya gene numuco wa urusoro - kandi agomba gukurikiza intambwe zose zubushakashatsi no gukemura ibibazo mugihe gikwiye, bikaba bitesha umutwe kuruta uko umuntu yabikora. tekereza.
Muri kiriya gihe, kubera ibiruhuko by'Ibiruhuko n'icyorezo, reagent zose zari zikenewe ntizari zihari, kandi twagombaga gushaka abantu ahantu hose kugira ngo tubagurize.Akazi ka buri munsi kwari ukugerageza, kugerageza, kohereza ingero no gushaka reagent.
Mu rwego rwo kwihutisha umwanya, itsinda ry’ubushakashatsi ryarenze uko bisanzwe bigenda, mugihe hategurwa hakiri kare intambwe ikurikira.Ariko ibi bivuze kandi ko niba hari ibitagenda neza mubyiciro byabanjirije, intambwe ikurikiraho itegurwa kubusa.
Nyamara, ubushakashatsi bwibinyabuzima ubwabwo ninzira isaba guhora mugeragezwa no kwibeshya.
Wu Guangming aracyibuka ko rimwe, muri vitro vector yakoreshejwe mu kwinjiza urutonde rwa ADN ya selile, ariko ntibyakoraga, bityo yagombaga guhindura reagent yibanze hamwe nibindi bipimo inshuro nyinshi akabikora inshuro nyinshi kugeza igihe bizabera yakoze.
Akazi kari gahangayikishije cyane kuburyo buriwese yakoraga cyane, bamwe mubanyamuryango bafite ibisebe mumunwa, ndetse bamwe bararushye kuburyo bashoboraga kwikubita hasi bakaganira kuko badashobora kwihagararaho.
Kugira ngo batsinde, Wu Guangming, yavuze kandi ko yagize amahirwe yo guhura n'itsinda rya bagenzi be b'indashyikirwa, kandi byari byiza kurangiza kubaka moderi y'imbeba mu gihe gito.
Urashaka kurushaho gutera imbere
Ku ya 6 Werurwe, imbeba zo mu gisekuru cya mbere 17 zavutse neza.Nyamara, ibi byasobanurwa gusa nkintambwe yambere yo kurangiza imirimo, byahise bikurikirwa nuburyo bukomeye bwo kwemeza no kohereza imbeba zabantu muri laboratoire ya P3 kugirango isuzume virusi.
Ariko, Wu Guangming yatekereje no kurushaho kunoza imiterere yimbeba.
Yatangarije abanyamakuru ko 80% by'abarwayi barwaye COVID-19 bafite ibimenyetso simusiga cyangwa barwaye byoroheje, bivuze ko bashobora kwishingikiriza ku budahangarwa bwabo kugira ngo bakire, mu gihe abandi 20% by'abarwayi barwara indwara zikomeye, cyane cyane ku bageze mu za bukuru cyangwa abafite indwara zishingiyeho. .Kubwibyo, kugirango dukoreshe neza kandi neza uburyo bwimbeba yimbeba mubijyanye na patologiya, ibiyobyabwenge, nubushakashatsi bwinkingo, iri tsinda ryibasiye imbeba zabantu zongeweho gusaza imburagihe, diyabete, hypertension, nubundi buryo bw’indwara zishingiye ku ndwara kugira ngo hashyizweho icyitegererezo cy’imbeba zikomeye.
Urebye ku mirimo ikomeye, Wu Guangming yavuze ko yishimiye ikipe nk'iyi, aho buri wese yasobanukiwe n'akamaro k'ibyo yakoraga, afite ubumenyi buke, kandi akora cyane kugira ngo agere kuri ibyo bisubizo.
Guhuza amakuru bijyanye:Ikipe ya Wu Guangming: "Icyorezo Cy’Intambara ya Guangdong Kubaha Intwari"
Igihe cyo kohereza: Kanama-02-2023